Analysis of P-Glycoprotein Transport Cycle Reveals a New Way to Identify Efflux Inhibitors

[Image: see text] P-glycoprotein (P-gp) is found to be of considerable interest for the design of drugs capable of treating chemoresistant tumors. This transporter is an interesting target for which an efficient approach has not yet been developed in terms of computer simulation. In this work, we us...

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Detalles Bibliográficos
Autores principales: Grigoreva, Tatyana A., Vorona, Svetlana V., Novikova, Daria S., Tribulovich, Vyacheslav G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713869/
https://www.ncbi.nlm.nih.gov/pubmed/36467933
http://dx.doi.org/10.1021/acsomega.2c04768

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713869/
https://www.ncbi.nlm.nih.gov/pubmed/36467933
http://dx.doi.org/10.1021/acsomega.2c04768

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