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Analysis of P-Glycoprotein Transport Cycle Reveals a New Way to Identify Efflux Inhibitors
[Image: see text] P-glycoprotein (P-gp) is found to be of considerable interest for the design of drugs capable of treating chemoresistant tumors. This transporter is an interesting target for which an efficient approach has not yet been developed in terms of computer simulation. In this work, we us...
Autores principales: | Grigoreva, Tatyana A., Vorona, Svetlana V., Novikova, Daria S., Tribulovich, Vyacheslav G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713869/ https://www.ncbi.nlm.nih.gov/pubmed/36467933 http://dx.doi.org/10.1021/acsomega.2c04768 |
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