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Identification of 3-Phenylquinoline Derivative PQ1 as an Antagonist of p53 Transcriptional Activity
[Image: see text] Transcription factor p53 regulates cellular responses to environmental perturbations via the transcriptional activation of downstream target genes. Inappropriate p53 activation can trigger abnormal cellular responses, therefore leading to acute or chronic tissue damage, human devel...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713874/ https://www.ncbi.nlm.nih.gov/pubmed/36467924 http://dx.doi.org/10.1021/acsomega.2c05891 |