Cargando…

Identification of 3-Phenylquinoline Derivative PQ1 as an Antagonist of p53 Transcriptional Activity

[Image: see text] Transcription factor p53 regulates cellular responses to environmental perturbations via the transcriptional activation of downstream target genes. Inappropriate p53 activation can trigger abnormal cellular responses, therefore leading to acute or chronic tissue damage, human devel...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Xingkang, Wang, Lu, Li, Zhenyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713874/ https://www.ncbi.nlm.nih.gov/pubmed/36467924 http://dx.doi.org/10.1021/acsomega.2c05891

Ejemplares similares

D'Amour, P.Q.; roman /
por: Godbout, Jacques, 1933-
Publicado: (1972)

7-Methoxy-2-phenylquinoline-3-carbaldehyde
por: Hayour, Hasna, et al.
Publicado: (2014)

Discovery of 2-Phenylquinolines with Broad-Spectrum Anti-coronavirus Activity
por: Nizi, Maria Giulia, et al.
Publicado: (2022)

Synthesis of Substituted 2-Pyridyl-4-phenylquinolines
por: Mamo, Antonino, et al.
Publicado: (2002)

3-Acetyl-2-methyl-4-phenylquinolin-1-ium chloride
por: Kiran, K., et al.
Publicado: (2010)

Ethyl 2-methyl-4-phenylquinoline-3-carboxylate
por: Bazgir, Ayoob
Publicado: (2009)

N-Isopropyl-6-methyl-2-phenylquinoline-3-carboxamide
por: Benzerka, Saida, et al.
Publicado: (2010)

Identification of 4-phenylquinolin-2(1H)-one as a specific allosteric inhibitor of Akt
por: Huang, Bill X., et al.
Publicado: (2017)

Discovery of 2-Phenylquinoline-4-Carboxylic Acid Derivatives as Novel Histone Deacetylase Inhibitors
por: Hui, Qian, et al.
Publicado: (2022)

Nonrestoration of spontaneously broken P and CP and PQ at high temperature
por: Dvali, G.R., et al.
Publicado: (1996)

3-Acetyl-6-chloro-4-phenylquinolin-2(1H)-one
por: Sundar, J. Kalyana, et al.
Publicado: (2009)

Ethyl 2,6-dichloro-4-phenylquinoline-3-carboxylate
por: Roopan, S. Mohana, et al.
Publicado: (2009)

4-Methyl-1-phenylquinolin-2(1H)-one
por: Petrov, Petar Yotov, et al.
Publicado: (2007)

4-Hydroxy-1-methyl-3-phenylquinolin-2(1H)-one
por: Kafka, Stanislav, et al.
Publicado: (2013)

Reduced transcriptional activity in the p53 pathway of senescent cells revealed by the MDM2 antagonist nutlin-3
por: Huang, Baoying, et al.
Publicado: (2009)

Bis(μ-2-phenylquinoline-4-carboxylato)bis[aqua(1,10-phenanthroline)(2-phenylquinoline-4-carboxylato)manganese(II)] dihydrate
por: Li, Wei-Wei, et al.
Publicado: (2011)

Methyl 6-chloro-2-methyl-4-phenylquinoline-3-carboxylate
por: Sundar, J. Kalyana, et al.
Publicado: (2009)

Ethyl 6-chloro-2-methyl-4-phenylquinoline-3-carboxylate
por: Subashini, R., et al.
Publicado: (2009)

Identification of LukPQ, a novel, equid-adapted leukocidin of Staphylococcus aureus
por: Koop, Gerrit, et al.
Publicado: (2017)

Identification of a Novel p.Q1772X ANK1 Mutation in a Korean Family with Hereditary Spherocytosis
por: Han, Joo Hyung, et al.
Publicado: (2015)

PhoPQ Regulates Quinolone and Cephalosporin Resistance Formation in Salmonella Enteritidis at the Transcriptional Level
por: Hu, Mengjun, et al.
Publicado: (2023)

3-(1-Adamantylamino)-3-methyl-1-phenylquinoline-2,4(1H,3H)-dione
por: Mahmoodi, Niusha, et al.
Publicado: (2009)

3-Acetyl-6-chloro-1-ethyl-4-phenylquinolin-2(1H)-one
por: Subashini, R., et al.
Publicado: (2009)

2-Bromo-5,7-dimethoxy-4-phenylquinoline
por: Gopal, Veshal, et al.
Publicado: (2009)

PQ, a new program for phylogeny reconstruction
por: Penzar, Dmitry, et al.
Publicado: (2018)

The Paeonia qiui R2R3-MYB Transcription Factor PqMYBF1 Positively Regulates Flavonol Accumulation
por: Zhang, Yue, et al.
Publicado: (2023)

Evaluating the role of NTHL1 p.Q90* allele in inherited breast cancer predisposition
por: Kumpula, Timo, et al.
Publicado: (2020)

(E)-1-(2-Methyl-4-phenylquinolin-3-yl)-3-phenylprop-2-en-1-one
por: Loh, Wan-Sin, et al.
Publicado: (2011)

6-Chloro-2-(4-methoxyphenyl)-4-phenylquinoline
por: Saravanan, B., et al.
Publicado: (2013)

Arginine does not rescue p.Q188R mutation deleterious effect in classic galactosemia
por: Haskovic, Minela, et al.
Publicado: (2018)

Enhanced Method for the Synthesis and Comprehensive Characterization of 1-(4-Phenylquinolin-2-yl)propan-1-one
por: Rajendran, Satheeshkumar, et al.
Publicado: (2023)

Study on PQ/PMMA Photopolymer Films Fabricated by Solvent Casting
por: Hsieh, Yu-Hsiang, et al.
Publicado: (2022)

In Vitro and In Silico Biological Studies of 4-Phenyl-2-quinolone (4-PQ) Derivatives as Anticancer Agents
por: Chen, Yi-Fong, et al.
Publicado: (2023)

A Novel R2R3-MYB Transcription Factor PqMYB4 Inhibited Anthocyanin Biosynthesis in Paeonia qiui
por: Huo, Dan, et al.
Publicado: (2020)

Glycogen synthase kinase3 beta phosphorylates serine 33 of p53 and activates p53's transcriptional activity
por: Turenne, Gaetan A, et al.
Publicado: (2001)

3-(4-Chlorophenyl)-1-(2-methyl-4-phenylquinolin-3-yl)prop-2-en-1-one
por: Prasath, R., et al.
Publicado: (2011)

Mode of action of the 2-phenylquinoline efflux inhibitor PQQ4R against Escherichia coli
por: Machado, Diana, et al.
Publicado: (2017)

Severe Hypertriglyceridemia due to a novel p.Q240H mutation in the Lipoprotein Lipase gene
por: Soto, Angela Ganan, et al.
Publicado: (2015)

The effect of the chemical chaperone 4-phenylbutyrate on secretion and activity of the p.Q160R missense variant of coagulation factor FVII
por: Andersen, Elisabeth, et al.
Publicado: (2019)

CDK4 inhibition diminishes p53 activation by MDM2 antagonists
por: Sriraman, Anusha, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_bo1ol4vb7k2r55fhbd1su6avpn