Cargando…

Reevaluation of a Bicyclic Pyrazoline as a Selective 15-Lipoxygenase V-Type Activator Possessing Fatty Acid Specificity

[Image: see text] Regulation of lipoxygenase (LOX) activity is of great interest due to the involvement of the various LOX isoforms in the inflammatory process and hence many diseases. The bulk of investigations have centered around the discovery and design of inhibitors. However, the emerging under...

Descripción completa

Detalles Bibliográficos
Autores principales: van Hoorebeke, Christopher, Yang, Kevin, Mussetter, Samuel J., Koch, Grant, Rutz, Natalie, Lokey, R. Scott, Crews, Phillip, Holman, Theodore R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713885/
https://www.ncbi.nlm.nih.gov/pubmed/36467910
http://dx.doi.org/10.1021/acsomega.2c05877