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Reevaluation of a Bicyclic Pyrazoline as a Selective 15-Lipoxygenase V-Type Activator Possessing Fatty Acid Specificity
[Image: see text] Regulation of lipoxygenase (LOX) activity is of great interest due to the involvement of the various LOX isoforms in the inflammatory process and hence many diseases. The bulk of investigations have centered around the discovery and design of inhibitors. However, the emerging under...
Autores principales: | van Hoorebeke, Christopher, Yang, Kevin, Mussetter, Samuel J., Koch, Grant, Rutz, Natalie, Lokey, R. Scott, Crews, Phillip, Holman, Theodore R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713885/ https://www.ncbi.nlm.nih.gov/pubmed/36467910 http://dx.doi.org/10.1021/acsomega.2c05877 |
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