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5-Methoxyflavone alleviates LPS-mediated lung injury by promoting Nrf2-mediated the suppression of NOX4/TLR4 axis in bronchial epithelial cells and M1 polarization in macrophages

BACKGROUND: Acute lung injury (ALI) arises from sepsis or bacterial infection, which are life-threatening respiratory disorders that cause the leading cause of death worldwide. 5-Methoxyflavone, a methylated flavonoid, is gaining increased attention for its various health benefits. In the current st...

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Detalles Bibliográficos
Autores principales:	Liang, Panqiao, Wang, Linxin, Yang, Sushan, Pan, Xiping, Li, Jiashun, Zhang, Yuehan, Liang, Yueyun, Li, Jing, Zhou, Beixian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713965/ https://www.ncbi.nlm.nih.gov/pubmed/36451220 http://dx.doi.org/10.1186/s12950-022-00319-6

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