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NRP1 inhibition modulates radiosensitivity of medulloblastoma by targeting cancer stem cells

BACKGROUND: Medulloblastoma (MB) is the most common pediatric malignant brain tumor. Despite current therapies, the morbidity and recurrent risk remains significant. Neuropilin-1 receptor (NRP1) has been implicated in the tumor progression of MB. Our recent study showed that NRP1 inhibition stimulat...

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Detalles Bibliográficos
Autores principales: Douyère, Manon, Gong, Caifeng, Richard, Mylène, Pellegrini-Moïse, Nadia, Daouk, Joël, Pierson, Julien, Chastagner, Pascal, Boura, Cédric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9714111/
https://www.ncbi.nlm.nih.gov/pubmed/36457009
http://dx.doi.org/10.1186/s12935-022-02796-4