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NRP1 inhibition modulates radiosensitivity of medulloblastoma by targeting cancer stem cells
BACKGROUND: Medulloblastoma (MB) is the most common pediatric malignant brain tumor. Despite current therapies, the morbidity and recurrent risk remains significant. Neuropilin-1 receptor (NRP1) has been implicated in the tumor progression of MB. Our recent study showed that NRP1 inhibition stimulat...
Autores principales: | Douyère, Manon, Gong, Caifeng, Richard, Mylène, Pellegrini-Moïse, Nadia, Daouk, Joël, Pierson, Julien, Chastagner, Pascal, Boura, Cédric |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9714111/ https://www.ncbi.nlm.nih.gov/pubmed/36457009 http://dx.doi.org/10.1186/s12935-022-02796-4 |
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