Identifying novel interactions of the colon-cancer related APC protein with Wnt-pathway nuclear transcription factors

BACKGROUND: Colon cancer is often driven by mutations of the adenomatous polyposis coli (APC) gene, an essential tumor suppressor gene of the Wnt β-catenin signaling pathway. APC and its cytoplasmic interactions have been well studied. However, various groups have also observed its presence in the n...

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Detalles Bibliográficos
Autores principales: Al-Thani, Nayra M., Schaefer-Ramadan, Stephanie, Aleksic, Jovana, Mohamoud, Yasmin A., Malek, Joel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9714242/
https://www.ncbi.nlm.nih.gov/pubmed/36457029
http://dx.doi.org/10.1186/s12935-022-02799-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9714242/
https://www.ncbi.nlm.nih.gov/pubmed/36457029
http://dx.doi.org/10.1186/s12935-022-02799-1

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