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Identifying novel interactions of the colon-cancer related APC protein with Wnt-pathway nuclear transcription factors
BACKGROUND: Colon cancer is often driven by mutations of the adenomatous polyposis coli (APC) gene, an essential tumor suppressor gene of the Wnt β-catenin signaling pathway. APC and its cytoplasmic interactions have been well studied. However, various groups have also observed its presence in the n...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9714242/ https://www.ncbi.nlm.nih.gov/pubmed/36457029 http://dx.doi.org/10.1186/s12935-022-02799-1 |