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Identification of SNPs associated with methotrexate treatment outcomes in patients with early rheumatoid arthritis

Methotrexate is one of the cornerstones of rheumatoid arthritis (RA) therapy. Genetic factors or single nucleotide polymorphisms (SNPs) are responsible for 15%–30% of the variation in drug response. Identification of clinically effective SNP biomarkers for predicting methotrexate (MTX) sensitivity h...

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Detalles Bibliográficos
Autores principales: Kolan, Shrikant S., Li, Gaoyang, Grimolizzi, Franco, Sexton, Joe, Goll, Guro, Kvien, Tore K., Sundlisæter, Nina Paulshus, Zucknick, Manuela, Lillegraven, Siri, Haavardsholm, Espen A., Skålhegg, Bjørn Steen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9714492/
https://www.ncbi.nlm.nih.gov/pubmed/36467057
http://dx.doi.org/10.3389/fphar.2022.1075603