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Fisetin reduces the senescent tubular epithelial cell burden and also inhibits proliferative fibroblasts in murine lupus nephritis

Systemic lupus erythematosus (SLE) is a chronic autoimmune inflammatory disease characterized by the involvement of multiple organs. Lupus nephritis (LN) is a major risk factor for overall morbidity and mortality in SLE patients. Hence, designing effective drugs is pivotal for treating individuals w...

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Detalles Bibliográficos
Autores principales: Ijima, Shogo, Saito, Yuki, Nagaoka, Kentaro, Yamamoto, Sena, Sato, Tsukasa, Miura, Norihiro, Iwamoto, Taiki, Miyajima, Maki, Chikenji, Takako S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9714549/
https://www.ncbi.nlm.nih.gov/pubmed/36466895
http://dx.doi.org/10.3389/fimmu.2022.960601