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Fisetin reduces the senescent tubular epithelial cell burden and also inhibits proliferative fibroblasts in murine lupus nephritis
Systemic lupus erythematosus (SLE) is a chronic autoimmune inflammatory disease characterized by the involvement of multiple organs. Lupus nephritis (LN) is a major risk factor for overall morbidity and mortality in SLE patients. Hence, designing effective drugs is pivotal for treating individuals w...
Autores principales: | Ijima, Shogo, Saito, Yuki, Nagaoka, Kentaro, Yamamoto, Sena, Sato, Tsukasa, Miura, Norihiro, Iwamoto, Taiki, Miyajima, Maki, Chikenji, Takako S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9714549/ https://www.ncbi.nlm.nih.gov/pubmed/36466895 http://dx.doi.org/10.3389/fimmu.2022.960601 |
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