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Low-dose ganciclovir ameliorates dextran sulfate sodium-induced ulcerative colitis through inhibiting macrophage STING activation in mice

Ganciclovir (GCV) is a prodrug nucleoside analogue and is clinically used as antiviral drug for the treatment of cytomegalovirus (CMV) and other infections. Based on the potential anti-inflammatory activity of GCV, this study aimed to investigate the therapeutic effects of ganciclovir on dextran sul...

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Detalles Bibliográficos
Autores principales: Gong, Lin-Kong, Yang, Xiaodong, Yang, Juan, Wu, Shu, Chen, Yue, Zhang, Jiang-Tao, Wang, Zhi-Hong, Chen, Li-Hua, Xing, Chungen, Liu, Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9714675/
https://www.ncbi.nlm.nih.gov/pubmed/36467059
http://dx.doi.org/10.3389/fphar.2022.1020670