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Low-dose ganciclovir ameliorates dextran sulfate sodium-induced ulcerative colitis through inhibiting macrophage STING activation in mice
Ganciclovir (GCV) is a prodrug nucleoside analogue and is clinically used as antiviral drug for the treatment of cytomegalovirus (CMV) and other infections. Based on the potential anti-inflammatory activity of GCV, this study aimed to investigate the therapeutic effects of ganciclovir on dextran sul...
Autores principales: | Gong, Lin-Kong, Yang, Xiaodong, Yang, Juan, Wu, Shu, Chen, Yue, Zhang, Jiang-Tao, Wang, Zhi-Hong, Chen, Li-Hua, Xing, Chungen, Liu, Tong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9714675/ https://www.ncbi.nlm.nih.gov/pubmed/36467059 http://dx.doi.org/10.3389/fphar.2022.1020670 |
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