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Slow dynamics measured by phosphorescence lifetime reveals global conformational changes in human adult hemoglobin induced by allosteric effectors

The mechanism underlying allostery in hemoglobin (Hb) is still not completely understood. Various models describing the action of allosteric effectors on Hb function have been published in the literature. It has also been reported that some allosteric effectors—such as chloride ions, inositol hexaph...

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Detalles Bibliográficos
Autores principales: Schay, Gusztáv, Fidy, Judit, Herenyi, Levente
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9714750/
https://www.ncbi.nlm.nih.gov/pubmed/36454779
http://dx.doi.org/10.1371/journal.pone.0278417