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Insulin increases sensory nerve density and reflex bronchoconstriction in obese mice

Obesity-induced asthma responds poorly to all current pharmacological interventions, including steroids, suggesting that classic, eosinophilic inflammation is not a mechanism. Since insulin resistance and hyperinsulinemia are common in obese individuals and associated with increased risk of asthma,...

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Detalles Bibliográficos
Autores principales: Calco, Gina N., Maung, Jessica N., Jacoby, David B., Fryer, Allison D., Nie, Zhenying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9714782/
https://www.ncbi.nlm.nih.gov/pubmed/36107629
http://dx.doi.org/10.1172/jci.insight.161898