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Insulin increases sensory nerve density and reflex bronchoconstriction in obese mice
Obesity-induced asthma responds poorly to all current pharmacological interventions, including steroids, suggesting that classic, eosinophilic inflammation is not a mechanism. Since insulin resistance and hyperinsulinemia are common in obese individuals and associated with increased risk of asthma,...
Autores principales: | Calco, Gina N., Maung, Jessica N., Jacoby, David B., Fryer, Allison D., Nie, Zhenying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9714782/ https://www.ncbi.nlm.nih.gov/pubmed/36107629 http://dx.doi.org/10.1172/jci.insight.161898 |
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