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Human striatal organoids derived from pluripotent stem cells recapitulate striatal development and compartments
The striatum links neuronal circuits in the human brain, and its malfunction causes neuronal disorders such as Huntington’s disease (HD). A human striatum model that recapitulates fetal striatal development is vital to decoding the pathogenesis of striatum-related neurological disorders and developi...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9714809/ https://www.ncbi.nlm.nih.gov/pubmed/36395338 http://dx.doi.org/10.1371/journal.pbio.3001868 |