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Human striatal organoids derived from pluripotent stem cells recapitulate striatal development and compartments

The striatum links neuronal circuits in the human brain, and its malfunction causes neuronal disorders such as Huntington’s disease (HD). A human striatum model that recapitulates fetal striatal development is vital to decoding the pathogenesis of striatum-related neurological disorders and developi...

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Detalles Bibliográficos
Autores principales: Chen, Xinyu, Saiyin, Hexige, Liu, Yang, Wang, Yuqi, Li, Xuan, Ji, Rong, Ma, Lixiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9714809/
https://www.ncbi.nlm.nih.gov/pubmed/36395338
http://dx.doi.org/10.1371/journal.pbio.3001868