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Hexapeptides from mammalian inhibitory hormone hunt activate and inactivate nematode reproduction

BACKGROUND: Biopurification has been used to disclose an evolutionarily conserved inhibitory reproductive hormone involved in tissue mass determination. A (rat) bioassay-guided physicochemical fractionation using ovine materials yielded via Edman degradation a 14-residue amino acid (aa) sequence. As...

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Detalles Bibliográficos
Autores principales: Hart, John E., Mohan, Sharad, Davies, Keith G., Ferneyhough, Ben, Clarke, Iain J., Hunt, John A., Shnyder, Steve D., Mundy, Christopher R., Howlett, David R., Newton, Russell P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9714824/
https://www.ncbi.nlm.nih.gov/pubmed/36454864
http://dx.doi.org/10.1371/journal.pone.0278049