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Urine-derived exosomes from individuals with IPF carry pro-fibrotic cargo

BACKGROUND: MicroRNAs (miRNA) and other components contained in extracellular vesicles may reflect the presence of a disease. Lung tissue, sputum, and sera of individuals with idiopathic pulmonary fibrosis (IPF) show alterations in miRNA expression. We designed this study to test whether urine and/o...

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Detalles Bibliográficos
Autores principales: Elliot, Sharon, Catanuto, Paola, Pereira-simon, Simone, Xia, Xiaomei, Shahzeidi, Shahriar, Roberts, Evan, Ludlow, John, Hamdan, Suzana, Daunert, Sylvia, Parra, Jennifer, Stone, Rivka, Pastar, Irena, Tomic-Canic, Marjana, Glassberg, Marilyn K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9714968/
https://www.ncbi.nlm.nih.gov/pubmed/36454035
http://dx.doi.org/10.7554/eLife.79543