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Amino acid transporter SLC38A5 regulates developmental and pathological retinal angiogenesis

Amino acid (AA) metabolism in vascular endothelium is important for sprouting angiogenesis. SLC38A5 (solute carrier family 38 member 5), an AA transporter, shuttles neutral AAs across cell membrane, including glutamine, which may serve as metabolic fuel for proliferating endothelial cells (ECs) to p...

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Detalles Bibliográficos
Autores principales: Wang, Zhongxiao, Yemanyi, Felix, Blomfield, Alexandra K, Bora, Kiran, Huang, Shuo, Liu, Chi-Hsiu, Britton, William R, Cho, Steve S, Tomita, Yohei, Fu, Zhongjie, Ma, Jian-xing, Li, Wen-hong, Chen, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9714971/
https://www.ncbi.nlm.nih.gov/pubmed/36454214
http://dx.doi.org/10.7554/eLife.73105