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Mitochondrial DNA mediates immunoparalysis of dendritic cells in sepsis via STING signalling

BACKGROUND: Mitochondrial DNA (mtDNA) is a potent activator for pro‐inflammatory response. Dendritic cells (DCs) are immunosuppressed in sepsis, whether mtDNA mediates immunoparalysis in sepsis remains unknown. METHODS: The mRNAs were assessed by qPCR. Flow cytometry was used to measure the expressi...

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Detalles Bibliográficos
Autores principales:	Tu, Qing, Li, Yi, Zhu, Jiali, Guo, Long, Liu, Chenchen, Liu, Lu, Yuan, Yuan, Zou, Yun, Chen, Feng, Yao, Liangfang, Li, Jinbao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9715356/ https://www.ncbi.nlm.nih.gov/pubmed/36106559 http://dx.doi.org/10.1111/cpr.13328

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