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A combination of midlife diabetes mellitus and the apolipoprotein E ε4 allele increase risk for cognitive decline
BACKGROUND: It has been suggested that diabetes mellitus (DM) and the apolipoprotein E (APOE) ε4 allele (APOE4) increase the risk for Alzheimer’s disease (AD) and cognitive decline. However, the evidence is sparse. We explored whether APOE4 status modulated the effects of midlife and late-life DM on...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9715424/ https://www.ncbi.nlm.nih.gov/pubmed/36466611 http://dx.doi.org/10.3389/fnagi.2022.1065117 |