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A combination of midlife diabetes mellitus and the apolipoprotein E ε4 allele increase risk for cognitive decline

BACKGROUND: It has been suggested that diabetes mellitus (DM) and the apolipoprotein E (APOE) ε4 allele (APOE4) increase the risk for Alzheimer’s disease (AD) and cognitive decline. However, the evidence is sparse. We explored whether APOE4 status modulated the effects of midlife and late-life DM on...

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Detalles Bibliográficos
Autores principales:	Lee, Boung Chul, Choe, Young Min, Suh, Guk-Hee, Choi, Ihn-Geun, Lee, Jun Ho, Kim, Hyun Soo, Hwang, Jaeuk, Yi, Dahyun, Kim, Jee Wook
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Aging Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9715424/ https://www.ncbi.nlm.nih.gov/pubmed/36466611 http://dx.doi.org/10.3389/fnagi.2022.1065117

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