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Simultaneous determination of diquat and its two primary metabolites in rat plasma by ultraperformance liquid chromatography–tandem mass spectrometry and its application to the toxicokinetic study

PURPOSE: This study aimed to develop and validate an ultraperformance liquid chromatography–tandem mass spectrometry to simultaneously determine diquat (DQ) and its two primary metabolites in rat plasma and its application to the toxicokinetic study. METHOD: The chromatographic separation of DQ and...

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Detalles Bibliográficos
Autores principales: Mao, Zhengsheng, Yu, Youjia, Sun, Hao, Wu, Chao, Jiang, Qiaoyan, Chu, Chunyan, Zhao, Chongwen, Zhou, Yujie, Zhang, Jinsong, Cao, Yue, Chen, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9715450/
https://www.ncbi.nlm.nih.gov/pubmed/36454415
http://dx.doi.org/10.1007/s11419-022-00623-z