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Abnormal expression of TSG-6 disturbs extracellular matrix homeostasis in chondrocytes from endemic osteoarthritis

Background and aims: Kashin-Beck disease (KBD) is a unique endemic osteochondropathy with unclear pathogenesis in China. T-2 toxin exposure has been identified as a significant risk factor of KBD. However, the mechanism of articular cartilage damage induced by T-2 toxin is a conundrum. We explored t...

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Detalles Bibliográficos
Autores principales: Ning, Yujie, Zhang, Pan, Zhang, Feiyu, Chen, Sijie, Liu, Yanli, Chen, Feihong, Wu, Yifan, Li, Shujin, Wang, Chaowei, Gong, Yi, Hu, Minhan, Huang, Ruitian, Zhao, Hongmou, Guo, Xiong, Wang, Xi, Yang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9715581/
https://www.ncbi.nlm.nih.gov/pubmed/36468025
http://dx.doi.org/10.3389/fgene.2022.1064565