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Wnt signaling directs human pluripotent stem cells into vascularized cardiac organoids with chamber-like structures

Heart diseases are leading cause of death around the world. Given their unique capacity to self-renew and differentiate into all types of somatic cells, human pluripotent stem cells (hPSCs) hold great promise for heart disease modeling and cardiotoxic drug screening. hPSC-derived cardiac organoids a...

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Detalles Bibliográficos
Autores principales: Liang, Po-Yu, Chang, Yun, Jin, Gyuhyung, Lian, Xiaojun, Bao, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9715615/
https://www.ncbi.nlm.nih.gov/pubmed/36466327
http://dx.doi.org/10.3389/fbioe.2022.1059243