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mRNA-LNP expressing PfCSP and Pfs25 vaccine candidates targeting infection and transmission of Plasmodium falciparum

Malaria is a deadly disease responsible for between 550,000 and 627,000 deaths annually. There is a pressing need to develop vaccines focused on malaria elimination. The complex lifecycle of Plasmodium falciparum provides opportunities not only to target the infectious sporozoite stage, introduced b...

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Detalles Bibliográficos
Autores principales: Hayashi, Clifford T. H., Cao, Yi, Clark, Leor C., Tripathi, Abhai K., Zavala, Fidel, Dwivedi, Garima, Knox, James, Alameh, Mohamad-Gabriel, Lin, Paulo J. C., Tam, Ying K., Weissman, Drew, Kumar, Nirbhay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9715627/
https://www.ncbi.nlm.nih.gov/pubmed/36456563
http://dx.doi.org/10.1038/s41541-022-00577-8