Intercellular transfer of activated STING triggered by RAB22A-mediated non-canonical autophagy promotes antitumor immunity

STING, an endoplasmic reticulum (ER) transmembrane protein, mediates innate immune activation upon cGAMP stimulation and is degraded through autophagy. Here, we report that activated STING could be transferred between cells to promote antitumor immunity, a process triggered by RAB22A-mediated non-ca...

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Detalles Bibliográficos
Autores principales: Gao, Ying, Zheng, Xueping, Chang, Boyang, Lin, Yujie, Huang, Xiaodan, Wang, Wen, Ding, Shirong, Zhan, Weixiang, Wang, Shang, Xiao, Beibei, Huo, Lanqing, Yu, Youhui, Chen, Yilin, Gong, Run, Wu, Yuanzhong, Zhang, Ruhua, Zhong, Li, Wang, Xin, Chen, Qiuyan, Gao, Song, Jiang, Zhengfan, Wei, Denghui, Kang, Tiebang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9715632/
https://www.ncbi.nlm.nih.gov/pubmed/36280710
http://dx.doi.org/10.1038/s41422-022-00731-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9715632/
https://www.ncbi.nlm.nih.gov/pubmed/36280710
http://dx.doi.org/10.1038/s41422-022-00731-w

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