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G protein-coupled receptor 151 regulates glucose metabolism and hepatic gluconeogenesis

Human genetics has been instrumental in identification of genetic variants linked to type 2 diabetes. Recently a rare, putative loss-of-function mutation in the orphan G-protein coupled receptor 151 (GPR151) was found to be associated with lower odds ratio for type 2 diabetes, but the mechanism behi...

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Detalles Bibliográficos
Autores principales: Bielczyk-Maczynska, Ewa, Zhao, Meng, Zushin, Peter-James H., Schnurr, Theresia M., Kim, Hyun-Jung, Li, Jiehan, Nallagatla, Pratima, Sangwung, Panjamaporn, Park, Chong Y., Cornn, Cameron, Stahl, Andreas, Svensson, Katrin J., Knowles, Joshua W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9715671/
https://www.ncbi.nlm.nih.gov/pubmed/36456565
http://dx.doi.org/10.1038/s41467-022-35069-9