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DNA methylation and hydroxymethylation characterize the identity of D1 and D2 striatal projection neurons
Neuronal DNA modifications differ from those in other cells, including methylation outside CpG context and abundant 5-hydroxymethylation whose relevance for neuronal identities are unclear. Striatal projection neurons expressing D1 or D2 dopamine receptors allow addressing this question, as they sha...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9715678/ https://www.ncbi.nlm.nih.gov/pubmed/36456703 http://dx.doi.org/10.1038/s42003-022-04269-w |