DNA methylation and hydroxymethylation characterize the identity of D1 and D2 striatal projection neurons

Neuronal DNA modifications differ from those in other cells, including methylation outside CpG context and abundant 5-hydroxymethylation whose relevance for neuronal identities are unclear. Striatal projection neurons expressing D1 or D2 dopamine receptors allow addressing this question, as they sha...

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Detalles Bibliográficos
Autores principales: Marion-Poll, Lucile, Roussarie, Jean-Pierre, Taing, Lieng, Dard-Dascot, Cloelia, Servant, Nicolas, Jaszczyszyn, Yan, Jordi, Emmanuelle, Mulugeta, Eskeatnaf, Hervé, Denis, Bourc’his, Déborah, Greengard, Paul, Thermes, Claude, Girault, Jean-Antoine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9715678/
https://www.ncbi.nlm.nih.gov/pubmed/36456703
http://dx.doi.org/10.1038/s42003-022-04269-w

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