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Identification of a novel peptide ligand for the cancer-specific receptor mutation EGFRvIII using high-throughput sequencing of phage-selected peptides

We report here the selection and characterization of a novel peptide ligand using phage display targeted against the cancer-specific epidermal growth factor tyrosine kinase receptor mutation variant III (EGFRvIII). This receptor is expressed in several kinds of cancer: ovarian cancer, breast cancer...

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Detalles Bibliográficos
Autores principales: Mansour, Sourour, Adhya, Indranil, Lebleu, Coralie, Dumpati, Rama, Rehan, Ahmed, Chall, Santu, Dai, Jingqi, Errasti, Gauthier, Delacroix, Thomas, Chakrabarti, Raj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9715707/
https://www.ncbi.nlm.nih.gov/pubmed/36456600
http://dx.doi.org/10.1038/s41598-022-25257-4