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Moonlighting chaperone activity of the enzyme PqsE contributes to RhlR-controlled virulence of Pseudomonas aeruginosa

Pseudomonas aeruginosa is a major cause of nosocomial infections and also leads to severe exacerbations in cystic fibrosis or chronic obstructive pulmonary disease. Three intertwined quorum sensing systems control virulence of P. aeruginosa, with the rhl circuit playing the leading role in late and...

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Detalles Bibliográficos
Autores principales: Borgert, Sebastian Roman, Henke, Steffi, Witzgall, Florian, Schmelz, Stefan, zur Lage, Susanne, Hotop, Sven-Kevin, Stephen, Steffi, Lübken, Dennis, Krüger, Jonas, Gomez, Nicolas Oswaldo, van Ham, Marco, Jänsch, Lothar, Kalesse, Markus, Pich, Andreas, Brönstrup, Mark, Häussler, Susanne, Blankenfeldt, Wulf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9715718/
https://www.ncbi.nlm.nih.gov/pubmed/36456567
http://dx.doi.org/10.1038/s41467-022-35030-w