Virtual screening and drug repositioning of FDA-approved drugs from the ZINC database to identify the potential hTERT inhibitors

The length of the telomeres is maintained with the help of the enzyme telomerase constituting of two components, namely, a core reverse transcriptase protein (hTERT) and RNA (hTR). It serves as a significant and universal cancer target. In silico approaches play a crucial role in accelerating drug d...

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Detalles Bibliográficos
Autores principales: Afzaal, Hasan, Altaf, Reem, Ilyas, Umair, Zaman, Shaiq Uz, Abbas Hamdani, Syed Damin, Khan, Saifullah, Zafar, Hajra, Babar, Mustafeez Mujtaba, Duan, Yongtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9715757/
https://www.ncbi.nlm.nih.gov/pubmed/36467041
http://dx.doi.org/10.3389/fphar.2022.1048691

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9715757/
https://www.ncbi.nlm.nih.gov/pubmed/36467041
http://dx.doi.org/10.3389/fphar.2022.1048691

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