Cargando…

Cms1 coordinates stepwise local 90S pre-ribosome assembly with timely snR83 release

Ribosome synthesis begins in the nucleolus with 90S pre-ribosome construction, but little is known about how the many different snoRNAs that modify the pre-rRNA are timely guided to their target sites. Here, we report a role for Cms1 in such a process. Initially, we discovered CMS1 as a null suppres...

Descripción completa

Detalles Bibliográficos
Autores principales: Lau, Benjamin, Beine-Golovchuk, Olga, Kornprobst, Markus, Cheng, Jingdong, Kressler, Dieter, Jády, Beáta, Kiss, Tamás, Beckmann, Roland, Hurt, Ed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9715914/
https://www.ncbi.nlm.nih.gov/pubmed/36417864
http://dx.doi.org/10.1016/j.celrep.2022.111684