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Bioenhancing effects of piperine and curcumin on triterpenoid pharmacokinetics and neurodegenerative metabolomes from Centella asiatica extract in beagle dogs

Centell-S is a water-soluble extract of Centella asiatica containing more than 80% w/w triterpenoid glycosides. Madecassoside and asiaticoside are two major components of the extract and can be converted into active metabolites, triterpenic acids in large mammal species. In this study, the pharmacok...

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Detalles Bibliográficos
Autores principales: Boonyarattanasoonthorn, Tussapon, Kongratanapasert, Teetat, Maiuthed, Arnatchai, Hamlin, Robert, Kijtawornrat, Anusak, Khemawoot, Phisit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9715946/
https://www.ncbi.nlm.nih.gov/pubmed/36456663
http://dx.doi.org/10.1038/s41598-022-24935-7