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Bioenhancing effects of piperine and curcumin on triterpenoid pharmacokinetics and neurodegenerative metabolomes from Centella asiatica extract in beagle dogs
Centell-S is a water-soluble extract of Centella asiatica containing more than 80% w/w triterpenoid glycosides. Madecassoside and asiaticoside are two major components of the extract and can be converted into active metabolites, triterpenic acids in large mammal species. In this study, the pharmacok...
Autores principales: | Boonyarattanasoonthorn, Tussapon, Kongratanapasert, Teetat, Maiuthed, Arnatchai, Hamlin, Robert, Kijtawornrat, Anusak, Khemawoot, Phisit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9715946/ https://www.ncbi.nlm.nih.gov/pubmed/36456663 http://dx.doi.org/10.1038/s41598-022-24935-7 |
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