Origin, distribution, and function of three frequent coding polymorphisms in the gene for the human P2X7 ion channel

P2X7, an ion channel gated by extracellular ATP, is widely expressed on the plasma membrane of immune cells and plays important roles in inflammation and apoptosis. Several single nucleotide polymorphisms have been identified in the human P2RX7 gene. In contrast to other members of the P2X family, n...

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Detalles Bibliográficos
Autores principales: Schäfer, Waldemar, Stähler, Tobias, Pinto Espinoza, Carolina, Danquah, Welbeck, Knop, Jan Hendrik, Rissiek, Björn, Haag, Friedrich, Koch-Nolte, Friedrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9715982/
https://www.ncbi.nlm.nih.gov/pubmed/36467077
http://dx.doi.org/10.3389/fphar.2022.1033135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9715982/
https://www.ncbi.nlm.nih.gov/pubmed/36467077
http://dx.doi.org/10.3389/fphar.2022.1033135

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