Somatic mutations of activating signalling, transcription factor, and tumour suppressor are a precondition for leukaemia transformation in myelodysplastic syndromes

The transformation biology of secondary acute myeloid leukaemia (AML) from myelodysplastic syndromes (MDSs) is still not fully understood. We performed paired self‐controlled sequencing, including targeted, whole exome, and single‐cell RNA sequencing, in a cohort of MDS patients to search for AML tr...

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Detalles Bibliográficos
Autores principales: Xu, Feng, Wu, Lin‐Yun, Guo, Juan, He, Qi, Zhang, Zheng, Li, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716205/
https://www.ncbi.nlm.nih.gov/pubmed/36380727
http://dx.doi.org/10.1111/jcmm.17613

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716205/
https://www.ncbi.nlm.nih.gov/pubmed/36380727
http://dx.doi.org/10.1111/jcmm.17613

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