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A yeast‐based tool for screening mammalian diacylglycerol acyltransferase inhibitors

Dysregulation of lipid metabolism is associated with obesity and metabolic diseases but there is also increasing evidence of a relationship between lipid body excess and cancer. Lipid body synthesis requires diacylglycerol acyltransferases (DGATs) which catalyze the last step of triacylglycerol synt...

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Detalles Bibliográficos
Autores principales: Gajdoš, Peter, Ledesma‐Amaro, Rodrigo, Nicaud, Jean‐Marc, Rossignol, Tristan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716225/
https://www.ncbi.nlm.nih.gov/pubmed/36479627
http://dx.doi.org/10.1002/mbo3.1334