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A yeast‐based tool for screening mammalian diacylglycerol acyltransferase inhibitors
Dysregulation of lipid metabolism is associated with obesity and metabolic diseases but there is also increasing evidence of a relationship between lipid body excess and cancer. Lipid body synthesis requires diacylglycerol acyltransferases (DGATs) which catalyze the last step of triacylglycerol synt...
Autores principales: | Gajdoš, Peter, Ledesma‐Amaro, Rodrigo, Nicaud, Jean‐Marc, Rossignol, Tristan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716225/ https://www.ncbi.nlm.nih.gov/pubmed/36479627 http://dx.doi.org/10.1002/mbo3.1334 |
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