B-cell Lymphoma 6 (BCL6): From Master Regulator of Humoral Immunity to Oncogenic Driver in Pediatric Cancers

B-cell lymphoma 6 (BCL6) is a protooncogene in adult and pediatric cancers, first identified in diffuse large B-cell lymphoma (DLBCL) where it acts as a repressor of the tumor suppressor TP53, conferring survival, protection, and maintenance of lymphoma cells. BCL6 expression in normal B cells is fu...

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Detalles Bibliográficos
Autores principales: McLachlan, Tabitha, Matthews, William C., Jackson, Evangeline R., Staudt, Dilana E., Douglas, Alicia M., Findlay, Izac J., Persson, Mika L., Duchatel, Ryan J., Mannan, Abdul, Germon, Zacary P., Dun, Matthew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716245/
https://www.ncbi.nlm.nih.gov/pubmed/36166198
http://dx.doi.org/10.1158/1541-7786.MCR-22-0567

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716245/
https://www.ncbi.nlm.nih.gov/pubmed/36166198
http://dx.doi.org/10.1158/1541-7786.MCR-22-0567

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