NET-Triggered NLRP3 Activation and IL18 Release Drive Oxaliplatin-Induced Peripheral Neuropathy

Oxaliplatin is an antineoplastic agent frequently used in the treatment of gastrointestinal tumors. However, it causes dose-limiting sensorimotor neuropathy, referred to as oxaliplatin-induced peripheral neuropathy (OIPN), for which there is no effective treatment. Here, we report that the elevation...

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Detalles Bibliográficos
Autores principales: Lin, Tongtong, Hu, Liang, Hu, Fan, Li, Kun, Wang, Chao-Yu, Zong, Li-Juan, Zhao, Ya-Qian, Zhang, Xiaotao, Li, Yan, Yang, Yang, Wang, Yu, Jiang, Chun-Yi, Wu, Xuefeng, Liu, Wen-Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716254/
https://www.ncbi.nlm.nih.gov/pubmed/36255412
http://dx.doi.org/10.1158/2326-6066.CIR-22-0197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716254/
https://www.ncbi.nlm.nih.gov/pubmed/36255412
http://dx.doi.org/10.1158/2326-6066.CIR-22-0197

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