Cargando…

Subcapsular Sinus Macrophages Promote Melanoma Metastasis to the Sentinel Lymph Nodes via an IL1α–STAT3 Axis

During melanoma metastasis, tumor cells originating in the skin migrate via lymphatic vessels to the sentinel lymph node (sLN). This process facilitates tumor cell spread across the body. Here, we characterized the innate inflammatory response to melanoma in the metastatic microenvironment of the sL...

Descripción completa

Detalles Bibliográficos
Autores principales: Virgilio, Tommaso, Bordini, Joy, Cascione, Luciano, Sartori, Giulio, Latino, Irene, Molina Romero, Daniel, Leoni, Cristina, Akhmedov, Murodzhon, Rinaldi, Andrea, Arribas, Alberto J., Morone, Diego, Seyed Jafari, S. Morteza, Bersudsky, Marina, Ottolenghi, Aner, Kwee, Ivo, Chiaravalli, Anna Maria, Sessa, Fausto, Hunger, Robert E., Bruno, Antonino, Mortara, Lorenzo, Voronov, Elena, Monticelli, Silvia, Apte, Ron N., Bertoni, Francesco, Gonzalez, Santiago F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716256/
https://www.ncbi.nlm.nih.gov/pubmed/36206577
http://dx.doi.org/10.1158/2326-6066.CIR-22-0225