BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma

Diffuse midline gliomas are uniformly fatal pediatric central nervous system cancers that are refractory to standard-of-care therapeutic modalities. The primary genetic drivers are a set of recurrent amino acid substitutions in genes encoding histone H3 (H3K27M), which are currently undruggable. The...

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Detalles Bibliográficos
Autores principales: Panditharatna, Eshini, Marques, Joana G., Wang, Tingjian, Trissal, Maria C., Liu, Ilon, Jiang, Li, Beck, Alexander, Groves, Andrew, Dharia, Neekesh V., Li, Deyao, Hoffman, Samantha E., Kugener, Guillaume, Shaw, McKenzie L., Mire, Hafsa M., Hack, Olivia A., Dempster, Joshua M., Lareau, Caleb, Dai, Lingling, Sigua, Logan H., Quezada, Michael A., Stanton, Ann-Catherine J., Wyatt, Meghan, Kalani, Zohra, Goodale, Amy, Vazquez, Francisca, Piccioni, Federica, Doench, John G., Root, David E., Anastas, Jamie N., Jones, Kristen L., Conway, Amy Saur, Stopka, Sylwia, Regan, Michael S., Liang, Yu, Seo, Hyuk-Soo, Song, Kijun, Bashyal, Puspalata, Jerome, William P., Mathewson, Nathan D., Dhe-Paganon, Sirano, Suvà, Mario L., Carcaboso, Angel M., Lavarino, Cinzia, Mora, Jaume, Nguyen, Quang-De, Ligon, Keith L., Shi, Yang, Agnihotri, Sameer, Agar, Nathalie Y.R., Stegmaier, Kimberly, Stiles, Charles D., Monje, Michelle, Golub, Todd R., Qi, Jun, Filbin, Mariella G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716260/
https://www.ncbi.nlm.nih.gov/pubmed/36305736
http://dx.doi.org/10.1158/2159-8290.CD-21-1491

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716260/
https://www.ncbi.nlm.nih.gov/pubmed/36305736
http://dx.doi.org/10.1158/2159-8290.CD-21-1491

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