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Heterozygous premature termination in zinc-finger domain of Krüppel-like factor 2 gene associates with dysregulated immunity

Krüppel-like factor 2 (KLF2) is a transcription factor with significant roles in development, maturation, differentiation, and proliferation of several cell types. In immune cells, KLF2 regulates maturation and trafficking of lymphocytes and monocytes. KLF2 participates in regulation of the nuclear...

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Detalles Bibliográficos
Autores principales: Pernaa, Nora, Keskitalo, Salla, Chowdhury, Iftekhar, Nissinen, Antti, Glumoff, Virpi, Keski-Filppula, Riikka, Junttila, Juhani, Eklund, Kari K., Santaniemi, Wenny, Siitonen, Sanna, Seppänen, Mikko RJ., Vähäsalo, Paula, Varjosalo, Markku, Åström, Pirjo, Hautala, Timo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716311/
https://www.ncbi.nlm.nih.gov/pubmed/36466816
http://dx.doi.org/10.3389/fimmu.2022.819929