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A Universal Eluent System for Method Scouting and Separation of Biotherapeutic Proteins by Ion-Exchange, Size-Exclusion, and Hydrophobic Interaction Chromatography

[Image: see text] Characterization and quality control of biotherapeutic proteins commonly require the application of several orthogonal separation techniques in order to establish product identity and purity. Many of the techniques used rely on a buffered aqueous mobile phase system to maintain the...

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Detalles Bibliográficos
Autores principales: Schwahn, Alexander B., Baek, Julia, Lin, Shanhua, Pohl, Christopher A., Cook, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716554/
https://www.ncbi.nlm.nih.gov/pubmed/36383642
http://dx.doi.org/10.1021/acs.analchem.2c03531